Alterations of Epigenetics and MicroRNAs in Cancer and Cancer Stem Cell

• मुख्य लेखक: Yoshimasa Saito (auth)
• स्वरूप: इलेक्ट्रोनिक पुस्तक अध्याय
• भाषा: अंग्रेज़ी
• प्रकाशित: Frontiers Media SA 2014
• श्रृंखला: Frontiers Research Topics
• विषय: Genetics (non-medical); MicroRNAs; cancer stem cells; Methylation; epigenetics; Cancer
• ऑनलाइन पहुंच: DOAB: download the publication; DOAB: description of the publication

Studies have shown that alterations of epigenetics and microRNAs (miRNAs) play critical roles in the initiation and progression of human cancer. Epigenetic silencing of tumor suppressor genes in cancer cells is generally mediated by DNA hypermethylation of CpG island promoter and histone modificatio...