AMP-Activated Protein Kinase Signalling

• Main Author: Neumann, Dietbert (auth)
• Other Authors: Viollet, Benoit (auth)
• Format: Electronic Book Chapter
• Language: English
• Published: MDPI - Multidisciplinary Digital Publishing Institute 2019
• Subjects: Biology, life sciences; n/a; HDACs; transcription; epigenetics; spermatozoa; par complex; A769662; MDCK; skeletal muscle; AID; phosphorylation; energy metabolism; monocytes; autophagy; CML; liver; hindlimb suspension; pregnancy; preeclampsia; gestational diabetes mellitus; CaMKK2; assisted reproduction techniques; nutrient-sensing signals; sonic hedgehog; protein acetylation; glycogen storage disease; AMPK; adenosine monophosphate-activated protein kinase; AICAR; indirect calorimetry; IL-1?; MyHC I(?); HDAC4/5; endothelial cells; infection; hepatocyte; p70S6K; lipid metabolism; host defense; exercise; kidney disease; heat shock protein; ?RIM; mycobacteria; activation loop; developmental origins of health and disease (DOHaD); CREB; TAK1; metabolic-inflammation; phenylephrine; AMP-activated protein kinase (AMPK); KATs; 2-methoxyestradiol; DNA methylation; NLRP3; pump; ?-linker; steatosis; AMPK kinase; stress; endothelial nitric-oxide synthase; vasodilation; adherent junctions; epithelial cells; glycogen; Akt; synaptic activation; cellular energy sensing; glucose uptake; transporter; co-expression; atrophy; nutrigenomics; motility; vasoconstriction; fatty acid oxidation; oxidative stress; AS160; membrane; histone modification; sirtuin 1 (SIRT1); chromatin remodeling; insulin signalling; dietary fatty acids; ULK; CMML; adaptive thermogenesis; mTOR; MDS; mechanical unloading; AML; endothelial function; medulloblastoma; PKA; adipose tissue; NAD⁺; membranes; nutrition; ZO-1; TBC1D4; adipocyte; soluble Adenylyl cyclase; metabolism; renin-angiotensin system; energy utilization; proteasome; differentiation; signaling; peroxisome proliferator-activated receptor gamma coactivator 1-? (PGC1?); hypertrophy; AMP-activated protein kinase; metabolic disease; LKB1; soleus muscle; macrophages; Immediate early genes; CBS; beiging; motor endplate remodeling; ionomycin; nectin-afadin; tight junctions; resveratrol; protein kinase B; regrowth; mitochondria; protein synthesis; energy deficiency; catechol-<i>O</i>-methyltransferase; fiber-type; microarrays; carrier; acetyl-CoA; hypertension; 3T3-L1; hypothalamus; food intake
• Online Access: DOAB: download the publication; DOAB: description of the publication

Starting from a kinase of interest, AMP-activated protein kinase (AMPK) has gone far beyond an average biomolecule. Being expressed in all mammalian cell types and probably having a counterpart in every eukaryotic cell, AMPK has attracted interest in virtually all areas of biological research. Struc...