Antibody Repertoire and Graft Outcome Following Solid Organ Transplantation

• Main Author: Ajay Kumar Baranwal (auth)
• Other Authors: Narinder K. Mehra (auth), Brian D. Tait (auth)
• Format: Electronic Book Chapter
• Language: English
• Published: Frontiers Media SA 2017
• Series: Frontiers Research Topics
• Subjects: Medicine; HLA matching; donor specific antibodies; antibody mediated rejection; B cell immunity; Graft outcome; solid organ transplantation; non HLA antibodies; MICA antibodies; antibody subclass
• Online Access: DOAB: download the publication; DOAB: description of the publication

The first real major breakthrough that laid the basis of HLA antibody detection in the field of solid organ transplantation, came with the introduction of the complement dependent cytotoxicity (CDC) test in 1964 by Terasaki and McClelland. Since then, methods for antibody detection have evolved rema...