Bioinformatics of Non-Coding RNAs with Applications to Biomedicine: Recent Advances and Open Challenges

• Auteur principal: Alessandro Lagana (auth)
• Autres auteurs: Alfredo Ferro (auth), Carlo Maria Croce (auth)
• Format: Électronique Chapitre de livre
• Langue: anglais
• Publié: Frontiers Media SA 2017
• Collection: Frontiers Research Topics
• Sujets: Biotechnology; CRISPR; CLIPseq; RNA Editing; bioinformatics; isomiRs; microRNA; siRNA; ncRNA; networks; RNAseq
• Accès en ligne: DOAB: download the publication; DOAB: description of the publication

The recent discovery of small and long non-coding RNAs (ncRNAs) has represented a major breakthrough in the life sciences. These molecules add a new layer of complexity to biological processes and pathways by revealing a sophisticated and dynamic interconnected system whose structure is just beginni...