Breaking the cycle: Attacking the malaria parasite in the liver

• Main Author: Thomas L. Richie (auth)
• Other Authors: Urszula Krzych (auth), Ute Frevert (auth)
• Format: Electronic Book Chapter
• Language: English
• Published: Frontiers Media SA 2015
• Series: Frontiers Research Topics
• Subjects: Medicine; CD8 T cell; Plasmodium; B cell; antigen-presenting cell; immune response; Malaria vaccine; hepatic microenvironment; CD4 T cell; animal model; adjuvants
• Online Access: DOAB: download the publication; DOAB: description of the publication

Despite significant progress in the global fight against malaria, this parasitic infection is still responsible for nearly 300 million clinical cases and more than half a million deaths each year, predominantly in African children less than 5 years of age. The infection starts when mosquitoes transm...