Cancer Metabolism: Molecular Targeting and Implications for Therapy

• 1. Verfasser: Shanmugasundaram Ganapathy-Kanniappan (auth)
• Format: Elektronisch Buchkapitel
• Sprache: Englisch
• Veröffentlicht: Frontiers Media SA 2017
• Schriftenreihe: Frontiers Research Topics
• Schlagworte: Medicine; Tumor microenvironment; metastasis; Cancer Metabolism; glycolysis; immunotherapy; epigenetic regulation; metabolic reprogramming; Warburg effect
• Online-Zugang: DOAB: download the publication; DOAB: description of the publication

Development of an effective anticancer therapeutic necessitates the selection of cancer-related or cancer-specific pathways or molecules that are sensitive to intervention. Several such critical yet sensitive molecular targets have been recognized, and their specific antagonists or inhibitors valida...