CD1- and MR1-restricted T Cells in Antimicrobial Immunity

• Main Author: S.M. Mansour Haeryfar (auth)
• Other Authors: Thierry Mallevaey (auth)
• Format: Electronic Book Chapter
• Language: English
• Published: Frontiers Media SA 2016
• Series: Frontiers Research Topics
• Subjects: Medicine; CD1; MAIT cell; infection; immunopathology; microbes; inflammation; innate-like T cells; immunity; NKT cell; MR1
• Online Access: DOAB: download the publication; DOAB: description of the publication

Cell-mediated immunity to extracellular and intracellular microbes has been traditionally linked to CD4+ and CD8+ T cells that recognize pathogen-derived peptides in the context of major histocompatibility complex (MHC) class II and class I molecules, respectively. Recent progress in our understandi...