CD4+ T cell differentiation in infection: amendments to the Th1/Th2 axiom

• Hoofdauteur: Carl G Feng (auth)
• Andere auteurs: Dragana Jankovic (auth)
• Formaat: Elektronisch Hoofdstuk
• Taal: Engels
• Gepubliceerd in: Frontiers Media SA 2015
• Reeks: Frontiers Research Topics
• Onderwerpen: Medicine; Infection; Dendritic Cells; Cytokines; Immunoregulation; CD4 lymphocytes; Memory; long noncoding RNA; Macrophages; Metabolism; Th1 Th2
• Online toegang: DOAB: download the publication; DOAB: description of the publication

CD4+ T lymphocytes play an essential role in host defense against bacterial, parasitic and viral infections. During infection, under the influence of intrinsic signals received through peptide-MHC/TCR interactions and extrinsic signals provided by pathogen-conditioned dendritic and other accessory c...