Cellular and molecular mechanisms of motor neuron death in amyotrophic lateral sclerosis

• 第一著者: Ricardo Tapia (auth)
• フォーマット: 電子媒体 図書の章
• 言語: 英語
• 出版事項: Frontiers Media SA 2015
• シリーズ: Frontiers Research Topics
• 主題: Neurosciences; trophic factors; motor neuron degeneration; skeletal; neuroinflammation; muscle; genetic expression; spinal cord; amyotrophic lateral sclerosis (ALS)
• オンライン･アクセス: DOAB: download the publication; DOAB: description of the publication

Amyotrophic lateral sclerosis (ALS), which was described since 1869 by Jean Martin Charcot, is a devastating neurodegenerative disease characterized by the selective and progressive loss of upper and lower motor neurons of the cerebral cortex, brainstem and the spinal cord. The cognitive process is...