The changing faces of glutathione, a cellular protagonist

• Main Author: Alfonso Pompella (auth)
• Other Authors: Alessandro Corti (auth)
• Format: Electronic Book Chapter
• Language: English
• Published: Frontiers Media SA 2015
• Series: Frontiers Research Topics
• Subjects: Pharmacology; redox regulation; Oxidative Stress; gamma-Glutamyltransferase; cellular thiols; Iron; Epigenetic regulation; Plants; Glutathione; glutathione S-transferases; Apoptosis
• Online Access: DOAB: download the publication; DOAB: description of the publication

Glutathione (GSH) has been described for a long time just as a defensive reagent against the action of toxic xenobiotics (drugs, pollutants, carcinogens), both directly and as a cofactor for GSH transferases. As a prototype antioxidant, it has been involved in cell protection from the noxious effect...