Control of Visceral Leishmaniasis by Immunotherapeutic and Prophylactic Strategies

• Main Author: Alexandre Barbosa Reis (auth)
• Other Authors: Hira L Nakhasi (auth), Jesus G Valenzuela (auth), Nahid Ali (auth)
• Format: Electronic Book Chapter
• Language: English
• Published: Frontiers Media SA 2015
• Series: Frontiers Research Topics
• Subjects: Medicine; Immuno modulator; Th1 response; Visceral leishmaniasis; Immunotherapy; Vaccine
• Online Access: DOAB: download the publication; DOAB: description of the publication

Visceral leishmaniasis (VL) or kala-azar is the most dreadful of all forms of leishmaniasis caused by Leishmania donovani in Old World and Leishmania chagasi and/or Leishmania infantum in New World affecting millions of people worldwide. In active VL, macrophages host the replicating amastigotes in...