Current Challenges in Modeling Cellular Metabolism

• Main Author: Daniel Machado (auth)
• Other Authors: Markus J. Herrgard (auth), Kai H. Zhuang (auth), Nikolaus Sonnenschein (auth)
• Format: Electronic Book Chapter
• Language: English
• Published: Frontiers Media SA 2016
• Series: Frontiers Research Topics
• Subjects: Biology, life sciences; computational methods; Metabolic Engineering; Cellular metabolism; Metabolic Regulation; modeling formalisms; Systems Biology; phenotype simulation; Mathematical Models
• Online Access: DOAB: download the publication; DOAB: description of the publication

Mathematical and computational models play an essential role in understanding the cellular metabolism. They are used as platforms to integrate current knowledge on a biological system and to systematically test and predict the effect of manipulations to such systems. The recent advances in genome se...