Danger Signals Triggering Immune Response and Inflammation

• Main Author: Sophie Paczesny (auth)
• Other Authors: Walter G. Land (auth), Abdulraouf Ramadan (auth)
• Format: Electronic Book Chapter
• Language: English
• Published: Frontiers Media SA 2017
• Series: Frontiers Research Topics
• Subjects: Medicine; damage-associated molecular pattern molecules (DAMPs); pathogen-associated molecular patterns (PAMPs); inflammation; immune cells; alarmins
• Online Access: DOAB: download the publication; DOAB: description of the publication

The immune system detects "danger" through a series of what we call pathogen-associated molecular patterns (PAMPs) or damage-associated molecular pattern molecules (DAMPs), working in concert with both positive and negative signals derived from other tissues. PAMPs are molecules associated...