Dual role of microglia in health and disease: pushing the balance towards repair

• Main Author: Liliana Bernardino (auth)
• Other Authors: Raquel Ferreira (auth)
• Format: Electronic Book Chapter
• Language: English
• Published: Frontiers Media SA 2015
• Series: Frontiers Research Topics
• Subjects: Neurosciences; neuronal repair; Neurodegenerative Diseases; Inflammation; Microglia; neuron-glia crosstalk
• Online Access: DOAB: download the publication; DOAB: description of the publication

Microglial cells play a vital role in the innate immune response occurring in the Central Nervous System (CNS). Under physiologic conditions, microglia dynamically patrol the brain parenchyma and participate in the remodeling of active neuronal circuits. Accordingly, microglia can boost synaptic pla...