Dual role of microglia in health and disease: pushing the balance towards repair

• Autor principal: Liliana Bernardino (auth)
• Otros Autores: Raquel Ferreira (auth)
• Formato: Electrónico Capítulo de libro
• Lenguaje: inglés
• Publicado: Frontiers Media SA 2015
• Colección: Frontiers Research Topics
• Materias: Neurosciences; neuronal repair; Neurodegenerative Diseases; Inflammation; Microglia; neuron-glia crosstalk
• Acceso en línea: DOAB: download the publication; DOAB: description of the publication

Microglial cells play a vital role in the innate immune response occurring in the Central Nervous System (CNS). Under physiologic conditions, microglia dynamically patrol the brain parenchyma and participate in the remodeling of active neuronal circuits. Accordingly, microglia can boost synaptic pla...