Endoplasmic Reticulcum and Its Role in Tumor Immunity

• Main Author: Marek Michalak (auth)
• Other Authors: Edwin Bremer (auth), Paul Eggleton (auth)
• Format: Electronic Book Chapter
• Language: English
• Published: Frontiers Media SA 2016
• Series: Frontiers Research Topics
• Subjects: Medicine; Autoimmunity; Angiogenesis; T-cell receptors; genome damage; phage display; Aminopeptidases; Grp170; Oxidoreductases; Vaccines; chaperones
• Online Access: DOAB: download the publication; DOAB: description of the publication

The endoplasmic reticulum (ER) is an organelle crucial to many cellular functions and processes, including the mounting of T-cell immune responses. Indeed, the ER has a well-established central role in anti-tumor immunity. Perhaps best characterized is the role of the ER in the processing of antigen...