Endoplasmic Reticulum Stress Response and Transcriptional Reprogramming

• Hoofdauteur: Kezhong Zhang (auth)
• Formaat: Elektronisch Hoofdstuk
• Taal: Engels
• Gepubliceerd in: Frontiers Media SA 2015
• Reeks: Frontiers Research Topics
• Onderwerpen: Genetics (non-medical); ER stress; Inflammation; Transcriptional reprogramming; Unfolded Protein Response; Metabolism; Oncogenes
• Online toegang: DOAB: download the publication; DOAB: description of the publication

Endoplasmic reticulum (ER) is an intracellular organelle responsible for protein folding and assembly, lipid and sterol biosynthesis, and calcium storage. A number of biochemical, physiological, or pathological stimuli can interrupt protein folding process, causing accumulation of unfolded or misfol...