Endoplasmic Reticulum Stress Response and Transcriptional Reprogramming

• Main Author: Kezhong Zhang (auth)
• Format: Electronic Book Chapter
• Language: English
• Published: Frontiers Media SA 2015
• Series: Frontiers Research Topics
• Subjects: Genetics (non-medical); ER stress; Inflammation; Transcriptional reprogramming; Unfolded Protein Response; Metabolism; Oncogenes
• Online Access: DOAB: download the publication; DOAB: description of the publication

Endoplasmic reticulum (ER) is an intracellular organelle responsible for protein folding and assembly, lipid and sterol biosynthesis, and calcium storage. A number of biochemical, physiological, or pathological stimuli can interrupt protein folding process, causing accumulation of unfolded or misfol...