The Epithelial-to-Mesenchymal Transition (EMT) in Cancer

• 1. Verfasser: Joëlle Roche (Ed.) (auth)
• Format: Elektronisch Buchkapitel
• Sprache: Englisch
• Veröffentlicht: MDPI - Multidisciplinary Digital Publishing Institute 2018
• Schlagworte: Biology, life sciences; PLK1; CK2; epigenetics; cancer therapy; chemoresistance; TGF-beta; metastasis; non-coding RNAs; exosomes; cancer; epithelial-to-pericyte transition (EPT); Epithelial-to-mesenchymal transition (EMT)
• Online-Zugang: DOAB: download the publication; DOAB: description of the publication

The epithelial-to-mesenchymal transition (EMT) is a highly dynamic process with multiple transitional states, by which epithelial cells can convert into a mesenchymal phenotype. This process involves loss of cellular adhesion and cellular polarity, and an improvement in migratory and invasive proper...