Evolution of NK-mediated target recognition under the pressure of physiologic or pathologic stimuli

• Autor principal: Miguel Lopez-Botet (auth)
• Outros Autores: Simona Sivori (auth), Daniel Olive (auth), Massimo Vitale (auth)
• Formato: Recurso Electrónico Capítulo de Livro
• Idioma: inglês
• Publicado em: Frontiers Media SA 2015
• Colecção: Frontiers Research Topics
• Assuntos: Medicine; ILC; innate immunity; KIR; Autoimmune Diseases; decidual NK cell; NCR; anti-viral immune responses; anti-tumor immunity
• Acesso em linha: DOAB: download the publication; DOAB: description of the publication

Since their discovery NK cells have come out as potential tools to fight cancer and viruses. This finding early urged different groups to study the mechanisms governing NK cell function. The identification of the MHC-I-specific inhibitory receptors (i.e. KIRs, NKG2A and certain Ly49 molecules) allow...