Extracellular Nucleotides in the Regulation of Kidney Functions

• Main Author: Volker Vallon (auth)
• Other Authors: Robert John Unwin (auth), Helle Praetorius (auth), Bellamkonda K Kishore (auth)
• Format: Electronic Book Chapter
• Language: English
• Published: Frontiers Media SA 2015
• Series: Frontiers Research Topics
• Subjects: Physiology; purinergic receptors; Extracellular nucleotides; Adenosine; polycystic kidney disease; Pressure Diuresis; ATP release; Chronic Kidney Disease; Nitric Oxide; Angiotensin II; tubuloglomerular feedback
• Online Access: DOAB: download the publication; DOAB: description of the publication

ATP is normally regarded as the major source of fuel for the energy-demanding processes within cells; however, ATP and other nucleotides (such as ADP, UTP, UDP) can be released from cells, where they act as autocrine or paracrine signaling molecules to affect cellular and tissue functions. In respon...