G-quadruplex and Microorganisms

• Hoofdauteur: Richter, Sara N. (auth)
• Formaat: Elektronisch Hoofdstuk
• Taal: Engels
• Gepubliceerd in: MDPI - Multidisciplinary Digital Publishing Institute 2019
• Onderwerpen: Medicine; bacteria; folding; co-translational refolding; RecQ helicase; regulatory element; conformational dynamics; G4Hunter; NDPK; fluorescence; pseudorabies virus; Epstein-Barr virus (EBV); structure-activity relationship; PhenDC3; eukaryotic hosts; Herpesvirus; translation suppression; turn-on ligands; co-transcriptional folding; Herpesviridae; G-quadruplex; nucleoside diphosphate kinase; nucleic acids; nucleic acids conformation; bioinformatics; protein-DNA interaction; aptamers; deinococcus; Alphaherpesvirinae; EBNA1; G4; virus; human papillomaviruses; S. cerevisiae; genome stability; G-quadruplexes; metastable structure; genome evolution; pyridostatin; alphaherpesviruses; structure; protozoa; genome; G-quadruplex ligand; NMR; microbes; DNA; protein-mRNA interactions; G-quadruplex formation; immediate early promoters
• Online toegang: DOAB: download the publication; DOAB: description of the publication

G-quadruplexes (G4s) are nucleic acids secondary structures that form in DNA or RNA guanine (G)-rich strands. In recent years, the presence of G4s in microorganisms has attracted increasing interest. In prokaryotes, G4 sequences have been reported in several human pathogens. Bacterial enzymes able t...