Gene Silencing and Editing Strategies for Neurodegenerative Diseases

• Hoofdauteur: Clévio Nóbrega (auth)
• Andere auteurs: Sandro Alves (auth)
• Formaat: Elektronisch Hoofdstuk
• Taal: Engels
• Gepubliceerd in: Frontiers Media SA 2018
• Reeks: Frontiers Research Topics
• Onderwerpen: Neurosciences; Gene silencing; Long non-coding RNAs; RNA interference; Neurodegenerative diseases; CRISPR/Cas9; Neurodegeneration; Gene editing; Antisense oligonucleotides; Neuroinflammation; iPS cells
• Online toegang: DOAB: download the publication; DOAB: description of the publication

Neurodegenerative diseases (NDs) are a heterogeneous group of disorders affecting the central nervous system. Despite significant differences in their causes, neuropathological abnormalities, and clinical outcomes, some similarities can be found among them, as for example: 1) frequent aggregation an...