Golgi Pathology in Neurodegenerative Diseases

• Main Author: Catherine Rabouille (auth)
• Other Authors: Georg Haase (auth)
• Format: Electronic Book Chapter
• Language: English
• Published: Frontiers Media SA 2016
• Series: Frontiers Research Topics
• Subjects: Neurosciences; Neurodegenerative Diseases; Intracellular membrane traffic; Amyotrophic Lateral Sclerosis; signaling; Golgi fragmentation; Microtubules; Cell Death; Tethers; molecular motors; vesicles
• Online Access: DOAB: download the publication; DOAB: description of the publication

The Golgi apparatus is a central organelle that lies at the heart of the secretory pathway. It ensures post-translational protein modifications such as glycosylation and cleavage as well as protein sorting to neuronal axons and dendrites. Structural and functional alterations of the Golgi apparatus...