Harnessing oncolytic virus-mediated immunity

• Hoofdauteur: Volker Schirrmacher (auth)
• Andere auteurs: Philippe Fournier (auth)
• Formaat: Elektronisch Hoofdstuk
• Taal: Engels
• Gepubliceerd in: Frontiers Media SA 2015
• Reeks: Frontiers Research Topics
• Onderwerpen: Medicine; anti-tumor activity; immunovirotherapy; oncolytic virus; oncolytic virotherapy; tumor-associated antigen; immunotherapeutic approaches; anti-viral response
• Online toegang: DOAB: download the publication; DOAB: description of the publication

Oncolytic viruses (OVs) have emerged as a promising anticancer treatment. OVs selectively infect, replicate in, and kill tumor cells. Oncolytic viral therapy occurs in two phases: an initial phase where the virus mediates direct oncolysis of tumor cells, and a second phase where an induced post-onco...