How to improve immune reconstitution in allogeneic hematopoietic stem cell transplantation?

• मुख्य लेखक: Antoine Toubert (auth)
• अन्य लेखक: Hermann Einsele (auth)
• स्वरूप: इलेक्ट्रोनिक पुस्तक अध्याय
• भाषा: अंग्रेज़ी
• प्रकाशित: Frontiers Media SA 2015
• श्रृंखला: Frontiers Research Topics
• विषय: Medicine; cell therapy; Immune reconstitution; Haplo-SCT; HSCT; Thymic function
• ऑनलाइन पहुंच: DOAB: download the publication; DOAB: description of the publication

Allogeneic haematopoietic stem cell transplantation (allo-HSCT) is widely used in the treatment of haematological malignancies as a form of immunotherapy acting through a graft-versus-leukemia (GvL) reaction. This curative allogeneic response can be associated with severe drawbacks, such as frequent...