Human Tumor-Derived p53 Mutants: A Growing Family of Oncoproteins

TP53 gene mutations are present in more than half of all human cancers. The resulting proteins are mostly full-length with a single amino acid change and are abundantly expressed in cancer cells. Some of the mutant p53 proteins gain oncogenic functions (GOF) through which it actively contribute to t...

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Bibliografiset tiedot
Päätekijä: Giovanni Blandino (auth)
Muut tekijät: Ygal Haupt (auth)
Aineistotyyppi: Elektroninen Kirjan osa
Kieli:englanti
Julkaistu: Frontiers Media SA 2016
Sarja:Frontiers Research Topics
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