The Importance of Iron in Pathophysiologic Conditions

• Main Author: Raffaella Gozzelino (auth)
• Other Authors: Paolo Arosio (auth)
• Format: Electronic Book Chapter
• Language: English
• Published: Frontiers Media SA 2015
• Series: Frontiers Research Topics
• Subjects: Pharmacology; iron metabolism; iron and genetic disorder; iron and inflammation; Heme; iron and cardiotoxicity; Iron; iron and neurodegeneration; Iron deficiency and anemia
• Online Access: DOAB: download the publication; DOAB: description of the publication

The iron element (Fe) is strictly required for the survival of most forms of life, including bacteria, plants and humans. Fine-tuned regulatory mechanisms for Fe absorption, mobilization and recycling operate to maintain Fe homeostasis, the disruption of which leads to Fe overload or Fe depletion. W...