In-Cell NMR Spectroscopy: Biomolecular Structure and Function

• Main Author: Burz, David S. (auth)
• Other Authors: Shekhtman, Alexander (auth)
• Format: Electronic Book Chapter
• Language: English
• Published: MDPI - Multidisciplinary Digital Publishing Institute 2020
• Subjects: Biology, life sciences; protein NMR; time-resolved NMR; Ribosome; structural calculation 4; crystalline and amorphous starch; in-cell NMR; protein dynamics; DNP; protein modification; Tau; spectrum reconstruction 3; mRNA; Thioredoxin; protein structure; protein interactions; drug discovery; protein structure determination 1; review; enzyme activity; MARK2 phosphorylation; post-translational modifications; Dihydrofolate reductase; mammalian cells; target engagement; non-uniform sampling 2; paramagnetic effects; protein structure-function; cross-correlated relaxation; structure function; rRNA; 2D INADEQUATE; lipid membrane; Thymidylate synthase; whole cell NMR; enzyme kinetics; magic-angle spinning; live cell; solid-state NMR; Adenylate kinase; DNA; in-situ NMR; antimicrobial peptide; NMR spectroscopy; intrinsically disordered proteins
• Online Access: DOAB: download the publication; DOAB: description of the publication

This Special Issue examines state-of-the-art in-cell NMR spectroscopy as it relates to biological systems of increasing complexity. The compendia of research and recent innovations from prominent laboratories in the field of solid state and solution in-cell NMR spectroscopy, metabolomics and technol...