In-Cell NMR Spectroscopy: Biomolecular Structure and Function

This Special Issue examines state-of-the-art in-cell NMR spectroscopy as it relates to biological systems of increasing complexity. The compendia of research and recent innovations from prominent laboratories in the field of solid state and solution in-cell NMR spectroscopy, metabolomics and technol...

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Bibliographic Details
Main Author: Burz, David S. (auth)
Other Authors: Shekhtman, Alexander (auth)
Format: Electronic Book Chapter
Language:English
Published: MDPI - Multidisciplinary Digital Publishing Institute 2020
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Online Access:DOAB: download the publication
DOAB: description of the publication
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520 |a This Special Issue examines state-of-the-art in-cell NMR spectroscopy as it relates to biological systems of increasing complexity. The compendia of research and recent innovations from prominent laboratories in the field of solid state and solution in-cell NMR spectroscopy, metabolomics and technology development are presented. The work establishes in-cell NMR spectroscopy as the premier method for determining the structures and interaction capabilities of biological molecules at high resolution within the delicately intricate interior of living cells, and the means of utilizing cells as living laboratories to directly assess the effects of exogenous and endogenous stimuli on cell physiology.] 
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653 |a protein NMR 
653 |a time-resolved NMR 
653 |a Ribosome 
653 |a structural calculation 4 
653 |a crystalline and amorphous starch 
653 |a in-cell NMR 
653 |a protein dynamics 
653 |a DNP 
653 |a protein modification 
653 |a Tau 
653 |a spectrum reconstruction 3 
653 |a mRNA 
653 |a Thioredoxin 
653 |a protein structure 
653 |a protein interactions 
653 |a drug discovery 
653 |a protein structure determination 1 
653 |a review 
653 |a enzyme activity 
653 |a MARK2 phosphorylation 
653 |a post-translational modifications 
653 |a Dihydrofolate reductase 
653 |a mammalian cells 
653 |a target engagement 
653 |a non-uniform sampling 2 
653 |a paramagnetic effects 
653 |a protein structure-function 
653 |a cross-correlated relaxation 
653 |a structure function 
653 |a rRNA 
653 |a 2D INADEQUATE 
653 |a lipid membrane 
653 |a Thymidylate synthase 
653 |a whole cell NMR 
653 |a enzyme kinetics 
653 |a magic-angle spinning 
653 |a live cell 
653 |a solid-state NMR 
653 |a Adenylate kinase 
653 |a DNA 
653 |a in-situ NMR 
653 |a antimicrobial peptide 
653 |a NMR spectroscopy 
653 |a intrinsically disordered proteins 
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