Induction of Central Nervous System Disease by the Adaptive Immune Response

• Main Author: Fabienne Brilot (auth)
• Other Authors: Robert Weissert (auth)
• Format: Electronic Book Chapter
• Language: English
• Published: Frontiers Media SA 2017
• Series: Frontiers Research Topics
• Subjects: Medicine; autoimmune encephalitis; autophagy; aquaporin-4; multiple sclerosis; neuromyelitis optica spectrum disorder; T cell; thyroid gland; B cells; NMDA receptor; myelin oligodendrocyte glycoprotein
• Online Access: DOAB: download the publication; DOAB: description of the publication

Over the last years it has become evident that many neurological diseases of the central nervous system (CNS) are induced by a specific adaptive immune response directed against molecules expressed on CNS-resident cells. Well-recognized examples are anti-N-Methyl-D-Aspartate Receptor (NMDAR) encepha...