Influenza Virus and Vaccination

• Main Author: Nogales, Aitor (auth)
• Other Authors: DeDiego, Marta L. (auth)
• Format: Electronic Book Chapter
• Language: English
• Published: MDPI - Multidisciplinary Digital Publishing Institute 2020
• Subjects: Medicine; heterosubtypic immunity of influenza; master donor virus; imprinting; hemagglutinin; universal vaccines; pandemic; adaptive immunity; pregnant women; innate immunity; antibodies; Influenza vaccine; ARDS; influenza A virus; humoral response; influenza vaccine; original antigenic sin "OAS"; germinal centers; immunogenicity; lung; epitopes; Influenza virus; single nucleotide polymorphisms (SNPs); influenza virus; protein microarray assay; "universal" influenza vaccine; vaccination; influenza; multiple dimensional assay (MDA); infection; tissue resident; memory; vaccines; CD4 T cell; broad neutralizing antibody(bnAb); hemagglutinin (HA) of influenza virus; original antigenic sin; immune response; morbidity; T cell; mPLEX-Flu assay; Influenza A virus (IAV); virus-host interaction; hemagglutin stalk; memory B cells; vaccine safety; protection efficacy; live attenuated influenza vaccine; pediatrics; vaccination rate
• Online Access: DOAB: download the publication; DOAB: description of the publication

The influenza virus poses a threat to human health and is responsible for global epidemics every year. In addition to seasonal infections, influenza can cause occasional pandemics of great consequence when novel viruses are introduced into humans. Despite the implementation of comprehensive vaccinat...