Inhibiting PARP as a Strategic Target in Cancer
Poly-ADP ribose polymerase (PARP) proteins are critical mediators of DNA repair. Many traditional anti-cancer chemotherapy agents overwhelm a cell's ability to repair DNA damage in order to kill proliferating malignant cells. Recent evidence suggests that cancers within and across tissue types...
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Main Author: | Kristin Zorn (auth) |
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Other Authors: | Christina Annunziata (auth) |
Format: | Electronic Book Chapter |
Language: | English |
Published: |
Frontiers Media SA
2016
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Series: | Frontiers Research Topics
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Subjects: | |
Online Access: | DOAB: download the publication DOAB: description of the publication |
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