Investigating and harnessing T-cell functions with engineered immune receptors and their ligands

• Autor principal: Bruno Laugel (auth)
• Formato: Recurso Electrónico Capítulo de Livro
• Idioma: inglês
• Publicado em: Frontiers Media SA 2015
• Colecção: Frontiers Research Topics
• Assuntos: Medicine; T-cells; tcr; Immunosuppression; cancer immunotherapy; pMHC
• Acesso em linha: DOAB: download the publication; DOAB: description of the publication

T-cells are an essential component of the immune system that provide protection against pathogen infections and cancer and are involved in the aetiology of numerous autoimmune and autoinflammatory pathologies. Their importance in disease, the relative ease to isolate, expand and manipulate them ex v...