Lyme Disease: Recent Advances and Perspectives

• Main Author: Tanja Petnicki Ocwieja (auth)
• Other Authors: Catherine A Brissette (auth)
• Format: Electronic Book Chapter
• Language: English
• Published: Frontiers Media SA 2015
• Series: Frontiers Research Topics
• Subjects: Borrelia burgdorferi; innate immunity; adhesins; Tnseq; Eicosanoids; Lyme Disease; TLR; c di GMP; Ixodes scapularis; Lyme Arthritis
• Online Access: DOAB: download the publication; DOAB: description of the publication

The interplay between host and pathogen is a complex co-evolutionary battle of surveillance and evasion. The pathogen continuously develops mechanisms to subvert the immune response in order to establish infection while the immune system responds with novel mechanisms of detection. Because the major...