Macromolecular Structure Underlying Recognition in Innate Immunity

• Hoofdauteur: Uttara SenGupta (auth)
• Andere auteurs: Maha Ahmed Al-Mozaini (auth), Uday Kishore (auth)
• Formaat: Elektronisch Hoofdstuk
• Taal: Engels
• Gepubliceerd in: Frontiers Media SA 2018
• Reeks: Frontiers Research Topics
• Onderwerpen: Medicine; HIV-1; host-pathogen interactions; zebrafish model system; innate immunity; protein-protein interaction; complement; malaria; pattern recognition
• Online toegang: DOAB: download the publication; DOAB: description of the publication

Immune molecules have evolved to distinguish "self "molecules from "non-self", "altered self" and "danger" molecules. Recognition is mediated via interactions between pattern recognition receptor molecules (PPRs) and their ligands, which include hydrophobic an...