Matricellular Receptors as Potential Targets in Anti-Cancer Therapeutic Strategies

• Main Author: Herve Emonard (auth)
• Other Authors: Stephane Dedieu (auth), Laurent Duca (auth)
• Format: Electronic Book Chapter
• Language: English
• Published: Frontiers Media SA 2016
• Series: Frontiers Research Topics
• Subjects: Pharmacology; disco; Anti-cancer target
• Online Access: DOAB: download the publication; DOAB: description of the publication

The invasive character of a primary cancer is greatly dependent on numerous interactions between tumor cells and their extracellular surroundings. Matricellular receptors are defined as (cell-surface) receptors that bind extracellular matrix (ECM) structural proteins and soluble factors dynamically...