Metabolic Adaptation to Cell Growth and Proliferation in Normal and Pathological Conditions

• מחבר ראשי: Lluis Fajas (auth)
• מחברים אחרים: Albert Giralt (auth)
• פורמט: אלקטרוני Book Chapter
• שפה: אנגלית
• יצא לאור: Frontiers Media SA 2018
• סדרה: Frontiers Research Topics
• נושאים: Medicine; cancer metabolism; proliferation; mitochondria; lipogenesis; metabolic adaptation; obesity; Warburg effect
• גישה מקוונת: DOAB: download the publication; DOAB: description of the publication

Proliferating cells must adapt their metabolism to fulfill the increased requirements for energy demands and biosynthetic intermediates. This adaptation is particularly relevant in cancer, where sustained rapid proliferation combined with the harsh conditions of the tumor microenvironment represent...