The metabolic challenges of immune cells in health and disease

• Autor principal: Christian Frezza (auth)
• Outros Autores: Claudio Mauro (auth)
• Formato: Recurso Electrónico Capítulo de Livro
• Idioma: inglês
• Publicado em: Frontiers Media SA 2015
• Colecção: Frontiers Research Topics
• Assuntos: Medicine; metabolic syndrome; Obesity; Immunometabolism; TCA cycle; Glycolysis; macrophage; Inflammation; fatty acid oxidation; Pentose Phosphate Pathway; lymphocyte
• Acesso em linha: DOAB: download the publication; DOAB: description of the publication

Obesity and its co-morbidities, including atherosclerosis, insulin resistance and diabetes, are a world-wide epidemic. Inflammatory immune responses in metabolic tissues have emerged as a universal feature of these metabolic disorders. While initial work highlighted the contribution of macrophages t...