Mitochondria: the cell powerhouse and nexus of stress

• Main Author: Andrey V. Kuznetsov (auth)
• Other Authors: Sabzali Javadov (auth)
• Format: Electronic Book Chapter
• Language: English
• Published: Frontiers Media SA 2014
• Series: Frontiers Research Topics
• Subjects: Physiology; mitochondrial physiology; Oxidative Stress; Cell Death; Mitochondrial ion channels; mitochondrial metabolism
• Online Access: DOAB: download the publication; DOAB: description of the publication

Mitochondrion, a sub-cellular organelle originated from primary endosymbiosis, plays a vital role in energy metabolism of eukaryotic cells. The transfer of electrons through the electron transport chain (ETC) to molecular oxygen accompanied by the extrusion of protons from the matrix generate an ele...