Mobile Genetic Elements in Cellular Differentiation, Genome Stability, and Cancer

• Main Author: Jose Luis Garcia Perez (auth)
• Other Authors: Tammy A. Morrish (auth)
• Format: Electronic Book Chapter
• Language: English
• Published: Frontiers Media SA 2018
• Series: Frontiers Research Topics
• Subjects: Chemistry; transposon; genome stability; model organisms; reverse transcriptase; Mobile DNA; RNA-dependent DNA polymerase; cellular differentiation; retrotransposon; DNA repair
• Online Access: DOAB: download the publication; DOAB: description of the publication

The human genome, as with the genome of most organisms, is comprised of various types of mobile genetic element derived repeats. Mobile genetic elements that mobilize by an RNA intermediate, include both autonomous and non-autonomous retrotransposons, and mobilize by a "copy and paste" mec...