Model-Based Tools for Pharmaceutical Manufacturing Processes

Model-Based Tools for Pharmaceutical Manufacturing Processes

The Special Issue on "Model-Based Tools for Pharmaceutical Manufacturing Processes" will curate novel advances in the development and application of model-based tools to address ever-present challenges of the traditional pharmaceutical manufacturing practice as well as new trends. This boo...

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Bibliographic Details
Main Author: Gernaey, Krist V. (auth)
Other Authors: Schenkendorf, Rene (auth), Gerogiorgis, Dimitrios I. (auth), Mansouri, Seyed Soheil (auth)
Format: Electronic Book Chapter
Language:English
Published: MDPI - Multidisciplinary Digital Publishing Institute 2020
Subjects:
Medicine
n/a
sensitivity analysis
parametric probability-box
non-isothermal modelling
dynamic optimisation
batch-to-batch variation
pharmaceutical manufacturing
process kinetics
flowsheet modeling
continuous manufacturing
MATLAB Production Server
flexibility analysis
polynomial chaos
probabilistic design space
bypassing
ODE model
enzymatic reaction
enzymatic synthesis
parameter estimation
freeze-drying
reversible reaction
diffusion of innovation
multi-objective decision-making
software development
continuous stirred tank reactor
parenteral manufacturing
wet granulation
spectroscopic assay
process design
dynamic modelling
quality by design
Fourier analysis
residence time distribution
point estimate method
model integration
global optimization
robust process design
pharmaceutical processes
return on investment
Amoxicillin
pyrimidine-nucleoside phosphorylase
spray drying
single-use technology
global sensitivity analysis
process modeling
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Summary:The Special Issue on "Model-Based Tools for Pharmaceutical Manufacturing Processes" will curate novel advances in the development and application of model-based tools to address ever-present challenges of the traditional pharmaceutical manufacturing practice as well as new trends. This book provides a collection of nine papers on original advances in the model-based process unit, system-level, quality-by-design under uncertainty, and decision-making applications of pharmaceutical manufacturing processes.
Physical Description:1 electronic resource (188 p.)
ISBN:books978-3-03928-425-2
9783039284245
9783039284252
Access:Open Access

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