Molecular Basis of Cardiovascular Diseases: Implications of Natriuretic Peptides

• Main Author: Rubattu, Speranza (auth)
• Other Authors: Volpe, Massimo (auth)
• Format: Electronic Book Chapter
• Language: English
• Published: MDPI - Multidisciplinary Digital Publishing Institute 2019
• Subjects: Medicine; postmortem biochemistry; medulla; animal models; remodeling; BNP; PCSK9; guanylyl cyclase/natriuretic peptide receptor-A; cardiorenal syndrome; forensic medicine; preserved ejection fraction; kidney; renin-angiotensin-aldosterone system; atrial fibrillation; vasopressor; congestive heart failure; atrial natriuretic peptide; gene-knockout; obesity; heart failure; angiogenesis; adipose tissue; vascular; LDL receptor; metabolic syndrome; linkage analysis; cardiometabolic disease; cardiomyocyte; cardiac dysfunction; cardiac hypertrophy; insulin; lipid metabolism; cGMP; Idiopathic Pulmonary Arterial Hypertension (IPAH); Natriuretic Peptide Clearance Receptor (NPR-C) signaling; gene-duplication; renin-angiotensin system; natriuretic peptides; angiotensin receptor-neprilysin inhibitor; cardiac remodelling; ARNi; NT-proBNP; inflammation; pulmonary arterial hypertension; vascular homeostasis; endothelial cell; Atrial Natriuretic peptide; natriuretic peptide; vasodilator; stroke; genetic variants; arterial hypertension; fibroblast; MANP; hypertension; guanylyl cyclase receptor A
• Online Access: DOAB: download the publication; DOAB: description of the publication

The natriuretic peptides (NPs) family includes a class of hormones and their receptors needed for the physiological control of cardiovascular functions. The discovery of NPs provided a fundamental contribution into our understanding of the physiological regulation of blood pressure, and of heart and...