Molecular Dynamics at the Immunological Synapse

• मुख्य लेखक: Pedro Roda-Navarro (auth)
• अन्य लेखक: Andres Alcover (auth), Vincenzo Di Bartolo (auth)
• स्वरूप: इलेक्ट्रोनिक पुस्तक अध्याय
• भाषा: अंग्रेज़ी
• प्रकाशित: Frontiers Media SA 2017
• श्रृंखला: Frontiers Research Topics
• विषय: Medicine; cytoskeleton dynamics; intracellular signalling; Immunological Synapse; endosomal dynamics
• ऑनलाइन पहुंच: DOAB: download the publication; DOAB: description of the publication

The immunological synapse (IS) is a specialised cell-cell adhesion that mediates antigen acquisition and regulates the activation of lymphocytes. Initial studies of the IS showed a structure composed of stable supra-molecular activation clusters (SMAC) organised during the interaction of helper T ly...