Molecular Dynamics at the Immunological Synapse

• Glavni avtor: Pedro Roda-Navarro (auth)
• Drugi avtorji: Andres Alcover (auth), Vincenzo Di Bartolo (auth)
• Format: Elektronski Book Chapter
• Jezik: angleščina
• Izdano: Frontiers Media SA 2017
• Serija: Frontiers Research Topics
• Teme: Medicine; cytoskeleton dynamics; intracellular signalling; Immunological Synapse; endosomal dynamics
• Online dostop: DOAB: download the publication; DOAB: description of the publication

The immunological synapse (IS) is a specialised cell-cell adhesion that mediates antigen acquisition and regulates the activation of lymphocytes. Initial studies of the IS showed a structure composed of stable supra-molecular activation clusters (SMAC) organised during the interaction of helper T ly...