Molecular Dynamics at the Immunological Synapse

• Prif Awdur: Pedro Roda-Navarro (auth)
• Awduron Eraill: Andres Alcover (auth), Vincenzo Di Bartolo (auth)
• Fformat: Electronig Pennod Llyfr
• Iaith: Saesneg
• Cyhoeddwyd: Frontiers Media SA 2017
• Cyfres: Frontiers Research Topics
• Pynciau: Medicine; cytoskeleton dynamics; intracellular signalling; Immunological Synapse; endosomal dynamics
• Mynediad Ar-lein: DOAB: download the publication; DOAB: description of the publication

The immunological synapse (IS) is a specialised cell-cell adhesion that mediates antigen acquisition and regulates the activation of lymphocytes. Initial studies of the IS showed a structure composed of stable supra-molecular activation clusters (SMAC) organised during the interaction of helper T ly...