Molecular Mechanism of Alzheimer's Disease

Alzheimer's disease (AD) is an age-related neurological disease that affects tens of millions of people, in addition to their carers. Hallmark features of AD include plaques composed of amyloid beta, as well as neurofibrillary tangles of tau protein. However, despite more than a century of stud...

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Main Author: Macreadie, Ian (auth)
Format: Electronic Book Chapter
Language:English
Published: MDPI - Multidisciplinary Digital Publishing Institute 2019
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520 |a Alzheimer's disease (AD) is an age-related neurological disease that affects tens of millions of people, in addition to their carers. Hallmark features of AD include plaques composed of amyloid beta, as well as neurofibrillary tangles of tau protein. However, despite more than a century of study, the cause of Alzheimer's disease remains unresolved. The roles of amyloid beta and tau are being questioned and other causes of AD are now under consideration. The contributions of researchers, model organisms, and various hypotheses will be examined in this Special Issue. 
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653 |a calcium signaling 
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653 |a tau 
653 |a Prolyl isomerases 
653 |a NEAT1 
653 |a complement C3b/C4b receptor 
653 |a proteostasis 
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653 |a heat shock protein 
653 |a dendritic spine 
653 |a S-adenosylmethionine 
653 |a beta amyloid 
653 |a ion channel 
653 |a inflammation 
653 |a sleep fragmentation 
653 |a cystathionine-?-lyase CTH gene 
653 |a DNA methylation 
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653 |a microglia 
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653 |a therapy 
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