Molecular, Cellular and Model Organism Approaches for Understanding the Basis of Neurological Disease

• Autor principal: Robert J. Harvey (auth)
• Outros Autores: Kirsten Harvey (auth)
• Formato: Recurso Eletrônico Capítulo de Livro
• Idioma: inglês
• Publicado em: Frontiers Media SA 2017
• coleção: Frontiers Research Topics
• Assuntos: Neurosciences; Stem Cells; glycine receptor; Amyotrophic Lateral Sclerosis; Parkinson's disease; PET imaging; LRRK2; Zebrafish; Inflammation; GABA-A receptor; NMDA receptors; Intellectual Disability
• Acesso em linha: DOAB: download the publication; DOAB: description of the publication

The advent of next-generation sequencing technologies has resulted in a remarkable increase our understanding of human and animal neurological disorders through the identification of disease causing or protective sequence variants. However, in many cases, robust disease models are required to unders...