Molecular, Cellular and Model Organism Approaches for Understanding the Basis of Neurological Disease

• Main Author: Robert J. Harvey (auth)
• Other Authors: Kirsten Harvey (auth)
• Format: Electronic Book Chapter
• Language: English
• Published: Frontiers Media SA 2017
• Series: Frontiers Research Topics
• Subjects: Neurosciences; Stem Cells; glycine receptor; Amyotrophic Lateral Sclerosis; Parkinson's disease; PET imaging; LRRK2; Zebrafish; Inflammation; GABA-A receptor; NMDA receptors; Intellectual Disability
• Online Access: DOAB: download the publication; DOAB: description of the publication

The advent of next-generation sequencing technologies has resulted in a remarkable increase our understanding of human and animal neurological disorders through the identification of disease causing or protective sequence variants. However, in many cases, robust disease models are required to unders...