Multiscale Modeling of Cardiac Electrophysiology: Adaptation to Atrial and Ventricular Rhythm Disorders and Pharmacological Treatment

Multiscale modeling of cardiac electrophysiology helps to better understand the underlying mechanisms of atrial fibrillation, acute cardiac ischemia and pharmacological treatment. For this purpose, measurement data reflecting these conditions have to be integrated into models of cardiac electrophysi...

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Bibliographic Details
Main Author: Wilhelms, Mathias (auth)
Format: Electronic Book Chapter
Language:English
Published: KIT Scientific Publishing 2013
Series:Karlsruhe transactions on biomedical engineering / Ed.: Karlsruhe Institute of Technology / Institute of Biomedical Engineering
Subjects:
Online Access:DOAB: download the publication
DOAB: description of the publication
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520 |a Multiscale modeling of cardiac electrophysiology helps to better understand the underlying mechanisms of atrial fibrillation, acute cardiac ischemia and pharmacological treatment. For this purpose, measurement data reflecting these conditions have to be integrated into models of cardiac electrophysiology. Several methods for this model adaptation are introduced in this thesis. The resulting effects are investigated in multiscale simulations ranging from the ion channel up to the body surface. 
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653 |a acute cardiac ischemia 
653 |a parameter adaptation 
653 |a pharmacological therapy 
653 |a atrial fibrillation 
653 |a cardiac modeling 
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