Mysteries of Type I IFN response: benefits versus detriments

• मुख्य लेखक: Herbert Patrick Ludewick (auth)
• अन्य लेखक: Arno Mullbacher (auth), Yoichi Furuya (auth)
• स्वरूप: इलेक्ट्रोनिक पुस्तक अध्याय
• भाषा: अंग्रेज़ी
• प्रकाशित: Frontiers Media SA 2015
• श्रृंखला: Frontiers Research Topics
• विषय: Medicine; Autoimmunity; adjuvant; bacterial and viral infections; Vaccine; type I IFN
• ऑनलाइन पहुंच: DOAB: download the publication; DOAB: description of the publication

Successful containment of an infection is dependent on both innate and adaptive immune response. Cytokines are essential effectors of both of these systems. In particular, type I interferons (IFN-I) are important components of early innate immunity against an infection. However, the production of IF...