Never-resting microglia: physiological roles in the healthy brain and pathological implications

• Hoofdauteur: Amanda Sierra (auth)
• Andere auteurs: Marie-Eve Tremblay (auth), Hiroaki Wake (auth)
• Formaat: Elektronisch Hoofdstuk
• Taal: Engels
• Gepubliceerd in: Frontiers Media SA 2015
• Reeks: Frontiers Research Topics
• Onderwerpen: Neurosciences; phenotype; Neuroprotection; Disease; Health; Neurogenesis; Phagocytosis; Synapses; Microglia
• Online toegang: DOAB: download the publication; DOAB: description of the publication

Microglia are largely known as the major orchestrators of the brain inflammatory response. As such, they have been traditionally studied in various contexts of disease, where their activation has been assumed to induce a wide range of detrimental effects. In the last few years, a series of discoveri...