NK Cell-Based Cancer Immunotherapy

• Main Author: Susana Larrucea (auth)
• Other Authors: Rafael Solana (auth), Francisco Borrego (auth), Raquel Tarazona (auth)
• Format: Electronic Book Chapter
• Language: English
• Published: Frontiers Media SA 2016
• Series: Frontiers Research Topics
• Subjects: Medicine; NK cells; Cytokines; NK-92; CAR; cancer immunotherapy; adoptive cell therapy; ADCC
• Online Access: DOAB: download the publication; DOAB: description of the publication

Natural killer (NK) cells are innate lymphoid cells that have a significant role in regulating the defenses against cancer development and certain viral infections. They are equipped with an array of activating and inhibitory receptors that stimulate or diminish NK cell activity, respectively. Inhib...