Novel Therapeutic Targets and Emerging Treatments for Fibrosis

• Autor principal: Timothy D. Hewitson (auth)
• Outros Autores: Chrishan S. Samuel (auth)
• Formato: Recurso Electrónico Capítulo de Livro
• Idioma: inglês
• Publicado em: Frontiers Media SA 2018
• Colecção: Frontiers Research Topics
• Assuntos: Pharmacology; treatment strategies; Fibrosis; pharmacology; collagen; fibrogenesis; therapeutic targets
• Acesso em linha: DOAB: download the publication; DOAB: description of the publication

For decades we have known that the overgrowth, hardening and scarring of tissues (so-called fibrosis) represents the final common pathway and best histological predictor of disease progression in most organs. Fibrosis is the culmination of both excess extracellular matrix deposition due to ongoing o...